Education, Training and OutreachDue to its strongly cross-disciplinary character, our program provides excellent training grounds for students who will be facing challenges awaiting educators and scientists in the life sciences entering the 21st century workplace. We will utilize the unique opportunities that our multifaceted team of investigators offers, to develop an integrated research/education approach with the primary goal to prepare involved students to become "multilingual": to be able to communicate and thus, interact with scientists across disciplines and appreciate the true strength of the multidisciplinary approach to solving scientific problems. We will be aided in this undertaking by the experience of a number of the team members who have been and are being involved in specific federally funded educational and training programs. Our educational activity will be centered on five major components: curriculum development, student research programs, student/educator forums, special summer programs and outreach.
The Scientific Basis of Bioprinting
· The Differential Adhesion Hypothesis (DAH)
· Tissue Liquidity and Tissue Fusion
· Modeling Tissue Liquidity
· Principles of Accelerated Tissue Maturation
· Endothelial-Mesenchymal Transformation (EMT)
The Technological Aspects of Bioprinting
· The Bioink
· The Biopaper
· The Bioreactor
· Computer Aided Biological (CAB) Tools
· Technology Commercialization
CoursesGabor Forgacs (PI) has developed and taught a course entitled "Physics in Cell and Developmental Biology" for several years at the University of Missouri-Columbia. Since the course is offered to a diverse group of students from physics, chemistry, biology, engineering and the medical sciences, it was important to develop a framework in which the roles of these various disciplines in addressing a common set of biological phenomena could be appreciated. The course material, in conjunction with a reframing of the relation between physical and genetic processes in embryogenesis developed by Stuart Newman (Co-PI) and his colleagues, formed the basis of a book "Biological Physics of the Developing Embryo", Cambridge University Press (2005).
Ioan Kosztin (Co-PI) has developed "Computational Biological Physics", a course designed for graduate and advanced undergraduate students to provide an introduction to the main simulations techniques used in computational biology. These two courses will be adapted for utilization in summer programs at the lead institution (see below).
Glenn Prestwich (Co-PI) is among the founding faculty of a popular BS-MS program in Bioengineering at the University of Utah in which undergraduate bioengineering majors can obtain both degrees in five years; he currently has three students from this program in his lab.